Dihydromyricetin (DMY), also known as ampeloptin, is a natural flavonoid primarily extracted from the Japanese Raisin Tree (Hovenia dulcis) or the Ampelopsis grossedentata plant, commonly referred to as vine tea. It has garnered attention for its potential health benefits, including liver support, antioxidant activity, and hangover relief. For consumers and manufacturers in the UK, free samples of dihydromyricetin powder are often offered by suppliers to allow for evaluation of quality, purity, and formulation compatibility before committing to bulk purchases. These samples are typically available from suppliers and manufacturers who specialise in botanical extracts and healthcare supplement ingredients. This article provides a detailed overview of the types of dihydromyricetin powder samples available, key considerations for evaluation, and the processes for obtaining them, based exclusively on information from supplier documentation and product specifications.
Types of Dihydromyricetin Powder Free Samples
Free samples of dihydromyricetin powder are generally offered by suppliers to support formulation testing, consumer trials, and quality verification. The samples vary in concentration and formulation to meet different needs, from pure compound testing to application in functional foods or supplements.
Pure Dihydromyricetin Powder
A common type of free sample is a highly refined and concentrated form of DMY, typically containing 95–98% active compound with no added fillers or binders. This pure form is intended for professional formulations, clinical studies, or research purposes where high potency and minimal interference from other ingredients are required. Suppliers often provide this as a small quantity to assess solubility, stability, and efficacy in a controlled environment.
Standardized Extracts
Standardized extracts are another sample type, where each batch is tested to contain a consistent percentage of active dihydromyricetin. These extracts ensure reproducibility in supplements, clinical studies, or functional food applications. Specifications for these samples may include concentrations such as 10%, 20%, 30%, 50%, or 98%, depending on the supplier's offering. Standardization is crucial for maintaining quality and meeting regulatory requirements, as it allows for predictable dosing and performance in end products.
Solubility-Enhanced Formulations
Some suppliers offer samples of dihydromyricetin with improved solubility. Traditional dihydromyricetin has low water solubility, which can limit its absorption and efficacy in the body. Research indicates that only about 31% of dihydromyricetin may be fully utilized due to this issue. To address this, some suppliers develop modified forms, such as a 30% dihydromyricetin solubility specification, which is presented as a yellow-green powder. These samples are designed to help manufacturers and consumers test the enhanced bioavailability and integration into products like beverages or powders.
Multi-Sample Kits
While not explicitly detailed in the source material, some suppliers may offer sample kits that include various types or concentrations of dihydromyricetin powder. These kits allow for comparative testing of different grades or formulations to determine the best fit for a specific application. However, the availability of such kits is not confirmed in the provided documents, and interested parties should verify directly with suppliers.
Key Considerations When Evaluating Free Samples
When requesting and assessing free samples of dihydromyricetin powder, it is essential to focus on quality, consistency, and safety. The following factors, derived from supplier documentation, should be prioritised to ensure the product meets standards before any bulk order is placed.
Purity and Concentration
The effectiveness of dihydromyricetin is directly linked to its purity. High-quality DHM powder should have a clearly labelled purity level, commonly ranging from 95% to 98% in premium-grade products. When requesting free samples, it is advisable to specify the desired concentration to ensure the material meets formulation or research standards. Products that are standardized are preferable, as they guarantee a consistent percentage of active DHM across batches. Avoid samples with vague or missing purity data, as lower-grade powders may contain fillers or inactive compounds that dilute efficacy. For example, some suppliers offer specifications with purity levels from 10% to 98%, allowing for selection based on the intended use.
Sourcing and Quality Control
Dihydromyricetin is derived from natural sources, primarily the leaves of Ampelopsis grossedentata. Suppliers should provide transparent information about the origin and extraction method. Reliable suppliers often hold certifications such as ISO9001, ISO22000, GMP, HACCP, KOSHER, or HALAL, which indicate adherence to quality and safety standards. For instance, one supplier mentions a 100,000-level clean production workshop and non-additive, non-GMO processes. When evaluating samples, request a Certificate of Analysis (CoA) to verify purity, heavy metal content, and microbial safety—especially for pure and standardized forms used in professional formulations. This is crucial for ensuring the product is free from contaminants and suitable for consumption or further processing.
Solubility and Bioavailability
Given dihydromyricetin's low water solubility, which affects absorption, samples with enhanced solubility features should be considered. Suppliers may offer solubility-enhanced versions, such as those with a 30% solubility specification, to improve bioavailability. Testing these samples in relevant applications (e.g., liquid formulations or supplements) can help determine if the product delivers the intended benefits. The source material notes that only about 31% of dihydromyricetin is fully utilized in its traditional form, making solubility a key factor in sample evaluation.
Regulatory Compliance and Claims
All product claims should be substantiated and compliant with local health authority guidelines, such as those from the FDA or EFSA. Free samples should be labelled accurately, with clear information on usage, storage, and any health benefits. Suppliers should provide documentation supporting claims about antioxidant, antibacterial, or blood sugar-regulating properties. It is important to note that while research highlights these potential benefits, the samples themselves are for evaluation purposes and not intended for direct consumer use without proper formulation and regulatory approval.
Storage and Shelf Life
Proper storage is critical for maintaining sample quality. Dihydromyricetin powder should be stored in a cool, dry place, away from light, to preserve its potency. The shelf life for these products is typically up to 2 years when stored correctly. When receiving samples, check the packaging for any storage instructions and verify the expiry date to ensure the sample remains viable for testing.
How to Obtain Free Samples
The process for obtaining free samples of dihydromyricetin powder involves contacting suppliers directly, as these are typically offered by manufacturers or distributors rather than through consumer-facing programmes. Based on the source material, the following steps are generally applicable:
Identify Reputable Suppliers
Several suppliers are mentioned in the context documents, each offering dihydromyricetin powder samples. These include: - HealthKintai: Offers a free sample of 30% dihydromyricetin solubility powder, with specifications including CAS No. 27200-12-0, test method HPLC, lead time of 1–3 days, and shelf life of 2 years. Certifications include GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, and HALAL. - Runherb Inc.: Provides dihydromyricetin powder samples, with contact information for inquiries ([email protected]). The supplier emphasises the protective effects of dihydromyricetin on liver injury and offers samples for product development. - Xi'an Angel Biotechnology Co., Ltd. (Angelbio): Offers free samples of dihydromyricetin powder with specifications including concentrations from 10% to 98%, HPLC test method, and certifications such as ISO9001, Kosher, Halal, FDA, and IFEAT. The minimum order quantity (MOQ) for samples is 1 kg, and they are not for private person sale.
Contact the Supplier
To request a sample, visit the supplier's website or use the provided contact details. For example: - HealthKintai's product page indicates that a free sample is available, and the website includes a sample request option. - Runherb Inc. encourages potential customers to "Contact us now to get the main ingredient" via email. - Angelbio's page states "Free sample: Available" and provides a product inquiry form or contact information.
When contacting suppliers, specify the type and concentration of sample required (e.g., pure DHM or solubility-enhanced) and provide details about the intended use (e.g., formulation testing, consumer trial). Be prepared to share basic information such as company details or research objectives, as some suppliers may have eligibility criteria, such as being a manufacturer or researcher.
Understand Eligibility and Restrictions
The source material indicates that some samples are not for private person sale, suggesting that suppliers may prioritise business-to-business (B2B) transactions. For instance, Angelbio's MOQ is 1 kg, which may imply that samples are intended for commercial evaluation rather than individual use. However, other suppliers like HealthKintai do not specify such restrictions, so it is advisable to confirm eligibility when inquiring. There are no geographic restrictions mentioned in the source data, but suppliers are based in China, so international shipping, including to the UK, may involve additional costs or lead times. Payment terms for bulk orders may include T/T (telegraphic transfer), LC (letter of credit), or DA (documents against acceptance), but samples are typically offered free of charge, though shipping costs may apply.
Evaluate the Sample Upon Receipt
Once a sample is received, evaluate it based on the key considerations outlined earlier: purity, solubility, and quality control documentation. Test the sample in the intended application to assess performance. If the sample meets expectations, proceed with further discussions for bulk orders. If not, provide feedback to the supplier or explore alternative sources.
Potential Applications and Benefits
Dihydromyricetin samples are primarily used for research, formulation development, and quality assurance. The source material highlights several potential benefits that may be explored through sample testing:
- Liver Support: Studies indicate dihydromyricetin has a protective effect on liver injury in mice models, including ethanol-induced injury, by increasing reduced glutathione (GSH) levels and reducing malondialdehyde (MDA) and triacylglycerol (TG) levels. This suggests potential for use in liver health supplements.
- Antioxidant and Antibacterial Properties: The compound is noted for its antioxidant strength and antibacterial activity, making it suitable for functional foods or skincare products.
- Blood Sugar Regulation: Some research points to blood sugar-regulating properties, which could be relevant for dietary supplements aimed at metabolic health.
However, it is important to note that these benefits are based on laboratory and animal studies, and human clinical evidence may be limited. Free samples allow for preliminary testing to assess feasibility in specific applications.
Limitations and Considerations
While free samples provide an opportunity for evaluation, there are limitations based on the source material: - Sample Size: Samples are typically small quantities (e.g., enough for initial testing), and bulk orders require a minimum order quantity, such as 1 kg for Angelbio products. - Shipping and Costs: Suppliers may charge for shipping, especially for international delivery to the UK. The source material does not specify shipping costs for samples, so this should be confirmed when requesting. - Regulatory Context: In the UK, dihydromyricetin powder may be considered a novel food ingredient or a supplement ingredient, requiring compliance with UK food standards and labelling regulations. Free samples are for evaluation and not for sale or distribution to consumers without proper authorisation. - Source Reliability: The information is derived from supplier websites and product pages, which are authoritative for product specifications but may not include independent third-party verification. It is advisable to cross-reference with official regulatory databases if planning commercial use.
Conclusion
Free samples of dihydromyricetin powder offer a valuable opportunity for UK-based manufacturers, researchers, and formulators to assess the quality, purity, and suitability of this natural flavonoid for various applications. Key considerations include evaluating purity levels (typically 95–98% for premium grades), solubility features, and supplier certifications to ensure safety and efficacy. Suppliers such as HealthKintai, Runherb Inc., and Xi'an Angel Biotechnology provide samples upon request, though eligibility may favour business entities. When obtaining samples, it is essential to specify requirements, verify storage conditions, and test the product in the intended application. While the potential health benefits of dihydromyricetin are supported by preliminary research, samples are primarily for evaluation purposes, and any commercial use must comply with regulatory standards. For consumers seeking personal use, direct sample programmes are not detailed in the source material, and professional suppliers should be consulted for further guidance.